李喜红、科室主任

女，医学博士，主任医师，中信湘雅超声影像科主任。

2003年入职中信湘雅，任中国预防医学会出生缺陷预防与控制专业委员会产前超声诊断学组委员，中国超声医学工程学会生殖健康与优生优育超声专业委员会委员，中国超声医学工程学会非公医疗超声专业委员会委员，中华医学会计划生育学分会专科学组委员，湖南省健康服务业协会超声分会常务理事，湖南省超声医学工程学会理事。
湖南省医学会超声医学专业委员会妇产超声学组委员等。从事超声工作30余年，长期工作在临床一线，共诊断30余万例患者，擅长于应用三维超声对不孕症患者助孕前子宫内膜容受性、宫腔粘连、生殖道畸形、输卵管病变、卵巢肿块、助孕后妊娠及其并发症的超声评估。以第一作者或通讯作者在《Human Reproduction》 《Ultrasound in Obstetrics and Gynecology》 《Fertility and Sterility》等杂志共发表SCI论文30余篇，中文期刊11篇，国际生殖和妇产科超声会议收录摘要和会议发言70余篇，参编书籍3本。主持长沙市自然科学基金1项，省厅级课题1项，院内重大研究项目1项，院内临床研究项目3项。参与国家级、省市级、院内课题10余项。

一．主持或参加科研项目（课题）
1.长沙市自然科学基金，Kq2502263，早孕胚胎超声智能扫查方法研究：标准切面识别及生物学参数的自动化测量，2025/01-2027/12，主持
2.湖南省卫生计生委科研计划课题项目，C20180898，三维超声成像对不孕患者先天性子宫畸形诊断价值的研究，2018/01-2020/12，主持
3.中信湘雅生殖与遗传专科医院院内项目中青年骨干重点培养项目，三维超声成像对不孕症患者先天性子宫畸形诊断价值的研究，KYXM-201703，2017/01-2022/12，主持
4.中信湘雅生殖与遗传专科医院院内项目重大项目，面向实时动态影像的早孕期胚胎发育多参数智能评估，2023/08-2026/7，主持
5.中信湘雅生殖与遗传专科医院院内项目，IVF-ET后宫内外复合妊娠的风险因素及早期诊治的研究，YNXM-202310，2023/01-2025/12，主持
6.中信湘雅生殖与遗传专科医院院内项目，YNXM-201908，超声对子宫内膜容受性的评估价值及评分体系的构建，2020/01-2022/12，主持
7.国家自然科学基金青年基金，82302234，基于实时动态影像的早孕期胚胎发育多参数智能评估研究,2024/01-2026/12，参加 
8.湖南省自然科学基金面上项目，2024JJ5650，基于深度学习多参数特征数据智能评估早孕期胚胎发育的研究，2024/01-2026/12，参加 
9.湖南省自然科学基金青年基金，20201955，基于前瞻性队列的初次助孕结局影响因素及预测模型研究，参加
10.中国博士后科学基金面上项目，2019M652778，不同染色体核型异常胚胎早期发育的影像学研究，2019/01-2021/12，参加 
11.湖南省卫生计生委科研计划课题项目，C20180289，IVF-ET后胚胎发育早期的超声影像学特征与不良妊娠结局相关性的研究，2018/01-2020/12，参加
12.中信湘雅生殖与遗传专科医院院内项目，YNXM-202220，基于队列研究的助孕结局影响因素分析与预测模型的构建，2022/08-2025/08，参加

二．研究成果（论文）
英文：
1.Li X, Ouyang Y, Lu G. Value of transvaginal sonography in diagnosing heterotopic pregnancy after in vitro fertilization-embryo transfer. Ultrasound Obstet Gynecol, 2013,41(5):563-9.
2.Ouyang Y, Li X, Yi Y, Gong F, Lin G, Lu G. First-trimester diagnosis and management of Cesarean scar pregnancies after in vitro fertilization-embryo transfer: a retrospective clinical analysis of 12 cases. Reprod Biol Endocrinol, 2015;13:126.  
3.Ouyang Y, Tan Y, Yi Y, Gong F, Lin G, Li X*, Lu G*. Correlation between chromosomal distribution and embryonic findings on ultrasound in early pregnancy loss after IVF-embryo transfer. Hum Reprod, 2016,31(10):2212-8.    
4.Yi Y, Li X, Ouyang Y, Lin G, Lu G, Gong F. Discriminant analysis forecasting model of first trimester pregnancy outcomes developed by following 9,963 infertile patients after in vitro fertilization.FERTIL STERIL, 2016, 105(5):1261-5
5.Yi Y, Lu G, Ouyang Y, Lin G, Gong F, Li X*. A logistic model to predict early pregnancy loss following in vitro fertilization based on 2601 infertility patients. Reprod Biol Endocrinol 2016;14:15.
6.Li X, Ouyang Y, Yi Y, Tan Y, Lu G. Correlation analysis between ultrasound findings and abnormal karyotype in the embryos from early pregnancy loss after in vitro fertilization-embryo transfer. J Assist Reprod Genet, 2017, 34(1):43-50.
7. Li X#, Ouyang Y#, Yi Y, Lin G, Lu G, Gong F. Pregnancy outcomes of women with a congenital unicornuate uterus after in vitro fertilization-embryo transfer. Reproductive Biomedicine Online. 2017 Nov; 35(5):583-591  
8. Ouyang Y, Yi Y, Gong F, Lin G, Li X*. ESHRE–ESGE versus ASRM classifcation in the diagnosis of septate uterus: a retrospective study, Arch Gynecol Obstet. 2018 Oct;298(4):845-850    
9.Ouyang Y, Cai P, Gong F, Lin G, Qin J, Li X*. The risk of twin pregnancies should be minimized in patients with a unicornuate uterus undergoing IVF-ET. Sci Rep. 2020 Mar 27;10(1):5571.  
10.Ouyang Y, Qin J, Lin G, Xiang S, Li X*. Reference intervals of geatational sac, yolk sac, embryonic length, embryonic heart rate at 6-10 weeks after in vitro fertilization-embryo transfer. BMC Pregnancy Childbirth. 2020 Sep 14;20(1):533.   
11. Cai P, Ouyang Y, Gong F, Li X*. Pregnancy outcomes of dichorionic triamniotic triplet pregnancies after in vitro fertilization-embryo transfer: multifoetal pregnancy reduction versus expectant management. BMC Pregnancy Childbirth. 2020 Mar 17;20(1):165.
12. Liu L, Jiao Y, Li X*, Ouyang Y, Shi D. Machine learning algorithms to predict early pregnancy loss after in vitro fertilization-embryo transfer with fetal heart rate as a strong predictor. Comput Methods Programs Biomed. 2020 Jun 25;196:105624.
13. Ouyang Y, Chen H, Lin G, Xiang S, Qin J, Gong F, Li X*. Heterotopic Cesarean Scar Pregnancy: An Analysis of 20 Cases Following in vitro Fertilization-Embryo Transfer. J Ultrasound Med. 2021 Oct;40(10):2239-2249. doi: 10.1002/jum.15610. Epub 2021 Jan 20.  
14. P Cai, Y Ouyang, G Lin, Y Peng, J Qin, X Li*, F Gong*. Pregnancy outcomes of women with congenital uterus didelphys after in-vitro fertilization-embryo transfer. Ultrasound Obstet Gynecol. 2021 Aug 23.
15.Yan Ouyang, Hui Chen, Fei Gong, Ge Lin, Xihong Li*. Septum Resection Prior to In Vitro Fertilization-Embryo Transfer: A Retrospective Controlled Study. J Ultrasound Med. 2022 Nov 17. doi: 10.1002/jum.16128. Online ahead of print. 
16. Xihong Li, Pei Cai, Yan Ouyang*, Fei Gong. Heterotopic Interstitial Pregnancy: Early Ultrasound Diagnosis of 179 Cases after In Vitro Fertilization-Embryo Transfer. J Ultrasound Med. 2022 Sep 29. doi: 10.1002/jum.16103. Online ahead of print.   
17. Xihong Li#, Yangqin Peng#, Yuyao Mao, Yuan Li, Fei Gong, Yan Ouyang. Endometrial receptivity change: Ultrasound evaluation on ovulation day and transplantation day during the natural frozen embryo transfer cycle. Front. Endocrinol. 2023 Volume 14. doi: 10.3389/fendo.2023.1118044.  
18. Yan Ouyang, Yangqin Peng, Senmao Zhang, Fei Gong, Xihong L*. A simple scoring system for the prediction of early pregnancy loss developed by following 13,977 infertile patients after in vitro fertilization. Eur J Med Res 2023 Jul 14;28(1):237. doi: 10.1186/s40001-023-01218-z.  
19. Qingqing Wu, Xihong Li*, Li Li, Ouyang Yan, Qingwen He. Analysis of factors affecting ultrasound examination time: a quantitative study. Technology and Health Care. 2023 Aug 3. doi: 10.3233/THC-230406. Online ahead of print
20.Lijue Liu, Duo Tang, Xihong Li*, Yan Ouyang. Automatic fetal ultrasound image segmentation of first trimester for measuring biometric parameters based on deep learning. Multimedia Tools and Applications. 2023 https://doi.org/10.1007/s11042-023-16565-6
21. Y Ouyang#, J Xiao#, Q Wang, Y Wen, H Chen, F Gong, X Li*. Intramural twin pregnancy after in-vitro fertilization. Ultrasound Obstet Gynecol, 2024 Oct;64(4):553-555. 
22. Yan Ouyang#, Yangqin Peng#, Yuyao Mao, Mingxiang Zheng, Fei Gong, Yuan Li, Xihong Li*. An endometrial receptivity scoring system evaluated by ultrasonography in patients undergoing frozen-thawed embryo transfer: a prospective cohort study. Front Med (Lausanne), 2024 Mar 21:11:1354363.  
23. Yuyao Mao#, Yangqin Peng#, Mingxiang Zheng, Jingzi Xiao, Fei Gong, Xihong Li*, Yan Ouyang*. First-trimester ultrasound diagnosis and risk factor analysis of cesarean scar pregnancy after in vitro fertilization-embryo transfer. Quant Imaging Med Surg, 2024 Jul 1;14(7):5028-5039. 
24. Zheng, M#, Wen, Y#, Wang, H, Peng, Y, Fei, G, Hui, Ouyang, Y*, Li, X*. Diagnosis of 42 Cases of Intrauterine Twin Pregnancy Complicated With Ectopic Pregnancy: A Retrospective Cohort Study. J Ultrasound Med. 2024 Sep 27. doi: 10.1002/jum.16583. Online ahead of print. 
25. Zheng, M., Peng, Y., Cai, P., He, Q., Fei, G., Hui, C., Mao, Y., Li, X*, Ouyang, Y*. Surgical treatment of fallopian tubal pregnancy and interstitial pregnancy has no differential effect on intrauterine pregnancy after in vitro fertilization-embryo transfer. BMC Pregnancy Childbirth. 2024 Nov 18;24(1):762. 
26. Cai, P#. Zheng, M#. Wang, Q. Wen, Y. Chen, H. Gong, F. Lin, G. Li, X*, Ouyang, Y*. Diagnosis and management of heterotopic intramural pregnancy after in vitro fertilization: an eight-case series. Ultraschall in der Medizin, 2024 Aug 26. doi: 10.1055/a-2375-0319. Online ahead of print. 
27. Yuyao Mao, Yangqin Peng, Mingxiang Zheng, Pei Cai, Fei Gong, Hui Chen, Ge Lin, Yan Ouyang*, Xihong Li*. Is expectant management feasible for select patients diagnosed with a heterotopic tubal pregnancy following in vitro fertilization/intracytoplasmic sperm injection? BMC Pregnancy Childbirth. 2024 Dec 18;24(1):813.
28. Li W, Yang LJ, Xiong YY, Li ZS, Li X, Wen Y*. 4,5-Dimethoxycanthin-6-one Inhibits Glioblastoma Stem Cell and Tumor Growth by Inhibiting TSPAN1 Interaction with TM4SF1. Neurochem Res. 2024 Oct;49(10):2897-2909.
29. Tan Y, Gao Y, Lin G, Fu M, Li X, Yin X, Du J, Li J, Li W, Peng H, Yuan Y, Chen F, Jiang F, Zhang H, Lu G, Gong F, Wang W. Noninvasive prenatal testing (NIPT) in twin pregnancies with treatment of assisted reproductive techniques (ART) in a single center. Prenat Diagn. 2016;36(7):672-679.
30. Hai-Lan Ma, Fei Gong, Yi Tang, Xihong Li, Xiaofeng Li, Xiaoyi Yang, Guangxiu Lu. Inhibition of Endometrial Tiam1/Rac1 Signals Induced by miR-22 Up-Regulation Leads to the Failure of Embryo Implantation During the Implantation Window in Pregnant Mice.Biol Reprod. 2015 Jun;92(6):152. doi: 10.1095/biolreprod.115.128603. Epub 2015 Apr 29.
31.Gong F, Li X, Zhang S, Ma H, Cai S, Li J, Lin GE, Lu G. A modified ultra-long pituitary downregulation protocol improved endometrial receptivity and clinical outcome for infertile patients with polycystic ovarian syndrome. Exp Ther  Med. 2015 Nov;10(5):1865-1870. doi: 10.3892/etm.2015.2769. Epub 2015 Sep 23.
32.Chen Wang, Yangqin Peng, Hui Chen, Qinmei Wang, Yu Dong, Huimin Liu, Yaoshan Yao, Shunji Zhang, Yuan Li, Sufen Cai, Xihong Li, Ge Lin, Fei Gong. Early GnRH-agonist therapy does not negatively impact the endometrial repair process or live birth rate. Front Endocrinol (Lausanne). 2024 Apr 29:15:1343176. doi: 10.3389/fendo.2024.1343176. eCollection 2024.
33.Wu, Q., Ouyang, Y., Li, L., Liu, Y., Liu, J., Li, B., Li, X*. Building an ultrasound appointment system: focusing on instrument diversity and the scope of physician expertise. BMC medical informatics and decision making, (2025)25(1), 308. https://doi.org/10.1186/s12911-025-03150-0
34.Ouyang Y, Peng Y, Zheng M, Mao Y, Gong F, Li Y, Chen H, Li X*. The impact of intrauterine adhesions on endometrial receptivity in patients undergoing in vitro fertilization-embryo transfer. Front Endocrinol (Lausanne). 2025 Jan 21;15:1489839. doi: 10.3389/fendo.2024.1489839. Erratum in: Front Endocrinol (Lausanne). 2025 Mar 27;16:1585477. doi: 10.3389/fendo.2025.1585477. PMID: 39906037; PMCID: PMC11790458.
35.Peng Y, Zheng M, Mao Y, Gong F, Li Y, Chen H, Wang H, Ouyang Y, Li X*. Ultrasound evaluation of changes in endometrial receptivity from the day of ovulation to the day of transfer in patients with a history of intrauterine adhesions: a prospective cohort study. Quant Imaging Med Surg. 2025 May 1;15(5):4541-4556. doi: 10.21037/qims-24-2034. Epub 2025 Apr 16. PMID: 40384661; PMCID: PMC12084758.
36.Cai P, Zheng M, Peng Y, Mao Y, Gong F, Chen H, Lin G, Ouyang Y, Li X*. The effect of surgical treatment of tubal pregnancy on concurrent intrauterine pregnancy after in vitro fertilization. Sci Rep. 2025 Feb 5;15(1):4328. doi: 10.1038/s41598-025-88519-x. PMID: 39910263; PMCID: PMC11799342.
37. Zheng, M., Wang, H., Li, C., Ouyang, Y., Yan, L., Gong, F., Li, L., Li, X*. Marital Adjustment as a Mediator Between Emotional Suppression and Self-Compassion in Women Aged 35+ Undergoing In Vitro Fertilization-Embryo Transfer: A Cross-Sectional Observational Study. Depression and anxiety, 2025, 2100969. https://doi.org/10.1155/da/2100969

中文：
1.李喜红,陈辉,卢光琇.阴道超声对不孕症患者子宫内膜病变的诊断价值[J].中国医学工程, 2007, 15(1):3.
2.李喜红,刘薇,卢光琇.经阴道超声对早期异位妊娠的诊断价值[J].医学临床研究（2007).
3.李喜红,陈辉,龚斐,卢光琇. 经阴道超声诊断体外受精-胚胎移植后宫内双胎合并输卵管妊娠两例分析[J].医学临床研究, 2007, 24(3):3.
4.李喜红,欧阳妍,殷斌,卢光琇.早孕期经阴道超声检测卵黄囊对妊娠结局的预测价值[J].中国现代医学杂志, 2013, 23(30):4.
5.李喜红,殷斌，欧阳妍，卢光琇. 早孕期胎心率与妊娠结局的相关性. 中国现代医学杂志 23.28(2013):4.
6..欧阳妍,李喜红,卢光琇.体外受精-胚胎移植后经阴道超声对早期异位妊娠的诊断价值[J].中国现代医学杂志, 2011, 21(8):6.
7. 文益，欧阳妍，龚斐，王倩，李喜红 辅助生殖助孕后卵巢扭转的超声特点及病例报道，中国优生与遗传杂志，2020，28（11）：1393-1397。
8. 贺晴雯,李喜红#,欧阳妍,等.体外受精-胚胎移植女性病人医患信任现状及影响因素分析[J].全科护理,2021,19(26):3713-3716.
9. 贺晴雯,李喜红#.不孕女性患者婚姻调适、自尊与抑郁的相关性研究[J].当代护士(上旬刊),2023,30(12):74-77.DOI:10.19791/j.cnki.1006-6411.2023.34.020.
10.郑明香,刘芳,李喜红,刘俊，戴玲，周建伟*.住院冠心病患者健康信息素养现状及影响因素研究[J].湖南师范大学学报(医学版),2023,20(05):154-160.
11. 贺晴雯,欧阳妍,李喜红#.体外受精-胚胎移植患者早期流产的影响因素分析[J].中国性科学,2024,33(04):42-45.
12. 郑明香,黎丽,李喜红,李超凤，王恒旭，欧阳妍，周建伟*.接受体外受精-胚胎移植女性情绪抑制的相关因素[J].中国心理卫生杂志,2024,38(11):961-966.
13.文益，欧阳妍，姜毅博，龚斐，李喜红*，超声对辅助生殖助孕后卵巢扭转的漏误诊分析，现代医学前沿，第2卷（第7期），P74-79，2024
14. 贺晴雯,欧阳妍,李喜红#.体外受精-胚胎移植患者早期流产的影响因素分析[J].中国性科学,2024,33(04):42-45.

三．论著
1. 早期妊娠胎儿畸形超声诊断, 北京科学技术出版社，2020出版，参编
2. 正常胎儿神经系统发育超声解剖图谱，科学出版社，2022出版，参编（副主编）
3.胎儿颅脑与脊柱影像图解，北京科学技术出版社，2025出版，参编（主译）

四．专利
1. 刘译文;李喜红;欧阳妍;龚斐 一种诊疗床，实用新型, 授权，202321491536.9
2. 张娟;刘丽珏;李喜红;欧阳妍;吴青青;李仪;林戈;穆阳，一种根据B超检测中上彩血流图来计算孕早期胚胎胎心率的方法，发明专利, 授权,中国, CN201811470324.6
3. 欧阳妍;张森茂;李喜红;刘译文;彭扬琴;龚斐 外部干预行为的干预结果预测方法、装置和计算机设备,发明专利，CN202310243837.8
4.郑明香；欧阳妍；刘佳涛；李喜红；朱宁波；谭光华；龚斐 超声图像处理方法、装置、计算机设备和存储介质，发明专利，CN202510312291.6

五.奖励
1.李喜红，欧阳妍，卢光琇，湖南自然科学优秀学术论文，三等奖，湖南省科技厅，2014；
2.李喜红，欧阳妍，易妍，文益，殷斌，王倩，童朝晖，周灿，吴青青，熊开岚，3D超声成像技术在辅助生殖中的应用价值，第五届长沙市职工科技创新奖，二等奖，长沙市总工会，2017；
3.2018年获长沙市高级人才D类人才。
4.2019年获评长沙市高新区芙蓉标兵岗。
5.2017年和2021年获中信集团科研创新奖。
6.2024年获中信医疗学科建设奖。